I would guess no. I'm sure there's a picture or video out there somewhere that shows it but my assumption is the tire carrier latches closed to the hatch, so without the hatch down the tire carrier would just be flopping around. Not to say you couldn't figure out a way to use a strap to keep it "closed" with the hatch open if you really wanted to drive around like that. I know there was also talk about the tire carrier possibly being removable so that could be an option as well.Can you keep the glass up and close the tire Carrier?